Chart - you can draw at the chart
Starting Amount
$
After
years
Dividend yield
%
Dividends reinvested
$
Alnylam Pharmaceuticals, Inc.
Type
Public
Traded as NASDAQ: ALNY
Industry Pharmaceutical
Founded 2002
Headquarters Cambridge, MA, USA
Key people
John Maraganore, (CEO)
Number of employees
> 500 (2017)
Website Alnylam.com

Alnylam Pharmaceuticals is a biopharmaceutical company focused on the discovery, development and commercialization of RNA interference (RNAi) therapeutics for genetically defined diseases. The company was founded in 2002 and is headquartered in Cambridge, Massachusetts. In 2016, Forbes included the company on its "100 Most Innovative Growth Companies" list.

In 2002, Alnylam was founded by scientists Phillip Sharp, Paul Schimmel, David Bartel, Thomas Tuschl, and Phillip Zamore, and by investors Christoph Westphal and John Kennedy Clarke; John Maraganore was the founding CEO. The company was named after Alnilam, a star in Orion’s belt. The spelling was modified to make it unique. In 2003, the firm merged with the German pharmaceutical company, Ribopharma AG. The newly formed company also received $24.6 million in funding from private-equity firms. On February 27, 2004, Alnylam Pharmaceuticals filed for an IPO. The company raised $26 million and began trading as ALNY on the Nasdaq stock exchange.

In 2005, the company partnered with Medtronic to develop drug-device combinations to treat neurodegenerative disorders; and in 2006 with Biogen Idec to develop treatments of progressive multifocal leukoencephalopathy; In 2007, it entered into a nonexclusive alliance with Hoffmann-La Roche, in which Alnylam received $331 million in exchange for access to its technology platform. an dalso partnered with Isis Pharmaceuticals to found the company Regulus Therapeutics, focused on microRNA therapeutics.

In 2009, the company formed alliances with Cubist Pharmaceuticals and Kyowa Hakko Kirin to market a drug targeted at respiratory syncytial virus. In 2010, it expanded its previous collaboration with Medtronic to include the CHDI Foundation in its Huntington's Disease focused research . In 2011, it partnered with GlaxoSmithKline to develop RNAi technology enhancing vaccine production. The company entered into a 10-year alliance with Monsanto in 2012, to develop biotech solutions for the farming industry by developing natural molecules for crop protection. In 2012, it formed a partnership with Sanofi Genzyme to develop a treatment for transthyretin-mediated amyloidosis, a hereditary disease in Asia. In February 2013, it formed a partnership with The Medicines Company to develop a drug to treat a genetic form of high cholesterol.

In July 2013, during a Phase I trial Alnylam demonstrated statistically significant reduction of a protein called transthyretin, or TTR and demonstrated human efficacy with intravenous and subcutaneous modes of administration. In 2014, Sanofi Genzyme acquired a 12 percent stake in Alnylam and increased its rights to several of the company's drugs for $700 million. In a separate transaction Alnylam announced that it had purchased Merck & Co.'s Sirna Therapeutics, for $25 million cash and $150 million in stock. In 2015, the company had $41 million in revenue and a market cap of $5.2 billion.

In 2016, the company purchased land in Norton, Massachusetts to build a manufacturing facility.

In October 2016 the Phase III clinical trial of the company's lead product, revusiran, was halted due to increased deaths in the drug arm of the trial, and the company said it was terminating development of the compound.

In 2016, Alnylam Pharmaceuticals had 18 potential treatments in various development stages in Genetic Medicine, Cardio-Metabolic Disease and Hepatic Infectious Disease. In late 2016, the company's lead candidate in phase III studies was patisiran, a treatment targeting transthyretin (TTR) for the treatment of TTR-mediated amyloidosis (ATTR), in patients with familial amyloidotic polyneuropathy (FAP).

Investment goal date:
Dividends reinvested
Alnylam Pharmaceuticals, Inc. ALNY report Q3 2017
Period
Date
Adjusted Actuals EPS
GAAP EPS
Q1 2018
2018-05-04
--
--
Q4 2017
2018-02-12
--
--
Q4 2017
2018-02-06
--
--
Q3 2017
2017-11-07
--
--
Q3 2017
2017-11-07
-1.3400
0.0000
Q2 2017
2017-08-09
-1.3400
-1.3400
Q1 2017
2017-05-05
-1.2500
-1.2500
Q4 2016
2017-02-08
-1.3200
-1.3200
Q3 2016
2016-11-02
-1.2100
-1.2100
Q2 2016
2016-08-04
-1.0500
-1.0500
Q1 2016
2016-05-02
-1.2100
-1.2100
Q4 2015
2016-02-11
-1.0700
-1.0700
Q3 2015
2015-11-09
-0.9100
-0.9100
There is presents forecasts or rating agencies and recommendation for investors about this ticker
Funds
Fund Name
Ticker shares
BAILLIE GIFFORD & CO
3334511
BlackRock Fund Advisors
2100902
BlackRock Inc.
4746234
BlackRock Institutional Trust Company, N.A.
1953854
Blue Ridge Capital, L.L.C.
1590000
DODGE & COX
9399245
FMR LLC
12907883
GILDER GAGNON HOWE & CO LLC
1206049
GOLDMAN SACHS GROUP INC
1392594
PRICE T ROWE ASSOCIATES INC /MD/
4167969
Slate Path Capital LP
2000000
STATE STREET CORP
2166232
UBS GLOBAL ASSET MANAGEMENT AMERICAS INC
1731081
Vanguard Group, Inc
5660213
WELLINGTON MANAGEMENT CO LLP
12041179
Major Shareholders
Name Relationship
Total Shares
Holding stocks
NOVARTIS AG
5.3100% (4051002)
ALNY / IDIX /
SANOFI-AVENTIS
13.8200% (10554134)
ALNY / KBIO / REGN / RGLS /
ALNYLAM PHARMACEUTICALS, INC.
7.8900% (6021900)
ALNY / RGLS /
MARAGANORE JOHN
0.2000% (149710)
AGIO / ALNY / BLUE / RGLS /
BONNEY MICHAEL W
0.0100% (4000)
SHARP PHILIP A
0.2200% (165795)
ALNY /
SCHIMMEL PAUL
0.4000% (306996)
ALNY /
Greene Barry E
0.1300% (100428)
ACOR / ALNY / KPTI / RGLS /
Greene Barry E
0.2400% (185744)
ACOR / ALNY / KPTI / RGLS /
Vaishnaw Akshay
0.0100% (10625)
ALNY /
Vaishnaw Akshay
0.0600% (45201)
ALNY /
Reid Laurence
0.0200% (18103)
ALNY /
Mason Michael
0.0100% (5625)
ALNY /
% ()